It is not so easy. You could also say
With C# you have 2.5 x more problems than with Python.
Many factors account for why a specific amount of questions are asked. Popularity is just one of them.
And consider that a language/framework/pattern/IDE might be very new when another exists for years. In that time a lot more questions will be asked about the old one. Other factors might be how complex it is, how good the documentation is and so on.
For instance I am active in the SQL area. There seem to be way more MySQL questions than Oracle questions. In most cases this is because unexperienced users or hobby programmers use the free MySQL a lot more often than Oracle and have many newby questions that flood Stack Overflow.
There are really many factors to consider making it impossible to use tags as popularity indicator.