I often help beginners, which means that I am offering bits of advice (say, on how to break a problem into manageable, searchable pieces) on questions that end up being downvoted. This tends to result in the OP, horrified at losing a few points, deleting the question whilst I am preparing a comment or an answer. Thus, the gamification system discourages low-rep users from getting good answers and wastes the effort of people who have commented or who are in the process of answering.
Refreshing a deleted question, of course, brings up this message:
This question was voluntarily removed by its author.
This contains no way to offer the user the prepared advice (which, because of previous wasted efforts, I copy to clipboard before submitting). My strategy to mitigate this is to put Firefox into offline mode, click on the back button to see the questions list prior to the deletion, get back into online mode and click on the user's profile. From there, if they have other questions, I compress my offering into a comment and offer it there, if only so it is not wasted.
A better way to deal with this would be to show the user's handle on the deletion page, either for a preset duration (a day perhaps) or only for the session for users who had previously seen the question. This will make it easier to get in touch with the OP and ensure that the effort is not as wasted as it would otherwise be.
One could argue that the user's deletion shows that they are not bothered about being helped; that is undoubtedly true in some cases, but I'd suggest that we're also seeing a minor downside to gamification. In other words, the user's psychology has encouraged them to strenuously avoid losing imaginary internet currency even though getting an answer to their question should be more important to them.