Unsurprisingly, most long discussion threads under a post involve the OP — and preventing them from commenting on their own question or answer will help to reduce comments being used for discussion.
If the OP wants to discuss someone's comment, they should have the immediate option to 'take discussion to chat' instead, and be able to @reply from there.
Obviously this would change the commenting behaviour of the OP, but there may be a significant side benefit: a reduction is comments that solicit discussion from other users as we come to realise that we can't simply start a discussion thread on the post any more. All the 'correct' usages of comments would still work, as none usually require discussion:
- Request clarification from the author;
- Leave constructive criticism that guides the author in improving the post;
- Add relevant but minor or transient information to a post (e.g. a link to a related question, or an alert to the author that the question has been updated).