According to this announcement (is this the last announcement on the matter?), Markdown emphasis (bold or italics) inside a word is possible, as long as it does not happen directly next to a punctiation sign:
- If a single or double asterisk is supposed to be interpreted as intra-word emphasis, it cannot have punctuation on one side; it actually must be inside a word. An example of an edge case this solves is [...]
However, in posts (questions or answers), SE will happily render emphasized text after a dot:
- A /8 broadcast IPv4 address should end in 255. For example, 192.168.1.255
This does not work in comments, as can be seen in this picture:
Is there a way to emphasize text directly after a punctuation sign in a comment?
(Note: my initial use case for this feature was this comment, where I copied a line of HTML code and wanted to highlight la in <span class="i1">la</span>. It would be great to have a solution for that too, but I understand that that might be too much to ask from comment formatting).