On the cover, in large friendly letters, are the words "Don't Panic".
I'll admit, I'm a newb (I've been programming since June 2007 and I don't have ANY technical background at all), so perhaps I am completely unqualified to answer this, but here goes.
The reason I am not intimidated by most of this stuff is that a lot of it is completely unrelated to anything I need to do right now. I work predominantly on web stuff (and specifically on Flash and Flex), I use PHP, JS, HTML, CSS... Most of the questions here are completely beyond my scope. I view this as, "They know that, I know my field."
The thing that really gets me is that I don't know what I am supposed to be trying to learn half the time. I have never even heard a professor even say Olog2n, and I don't even own a textbook which describes "best practices" for OOP. I'm more or less forced to figure out all of this stuff on my own and I make a lot of mistakes because I have no idea what I am doing. I also really want to know C and C++ (and somewhere along the way master Java, Perl, and Python) but I don't even have a good place to start...
But, I'm not miffed. If anything, the very fact that I don't know any of this means that I am more likely to look at something new. If it looks like Greek, then my mouth drops and I center-click the tab. Otherwise it is a fascinating trip.
I also have in my favor a particular stubbornness, but mostly this is built on a knowledge that, in computer programming, "if you bang your head against a wall for long enough, the wall will move"