I have seen many questions on Stack Overflow and other sites on Area 51. I found that people use to down vote a question if it isn't related to that particular site but related to other Stack Exchange sister sites.
Personally, I find it quite rude to down vote new user's question when they are not aware about other sites (or don't understand where their question belongs).
I don't have a fool-proof solution to it but at least SO can block down votes when it is marked as Belong to SE sister sites (maybe new flag option). Also migrate the question to that sister site based on recommendation or automatically.
Below is an example of that kind of question: