It has no effect on questions less than or equal to 365 days.
The comment refers to the
If the question is more than 365 days old part where it says
has 1 or 0 comments - the commenter is saying if the OP adds 2 comments to his own question then it won't be subject to deletion after 365 days, however it may still be deleted if it meets all the conditions under the 30 days or 9 days policies, or a moderator deletes it, or enough high rep users vote to delete.
Basically - it can be deleted just as normal, but just not automatically under the 365 days policy.