I'm wasting a certain amount of time checking for possible responses to comments I'd specifically addressed to other participants about their own commentary, questions, or answers. During what time frame after their remarks is it reasonable to expect a response? (I'm thinking that a response within any given time might be in some inverse proportion to their overall "reputation", as highly-reputed participants would tend to spend enough time on their commentary &/or Q&A to have relatively little time left for such individualized responses.)
I think curiousdanii's comment is the main answer. But there are some tricks you might miss - I wasn't aware of them for a long time.
If you are requesting clarifying edits to questions, you might find the "favourites" feature useful. You can mark the questions as favourites, and you can sort the favourites list in your profile by "activity". Then you don't need to check for edits on each individual question.
With regard to comments, hopefully the user will know to ping you. Some new users don't; that's the biggest problem I can think of here.
Edits to answers will also bump a question to the top of your favourites list (correct me if I'm wrong). I don't think there is a convenient way to watch a specific answer; you just have to watch the whole question.
Or maybe you just mean "how often should I open StackExchange so I can check my inbox" (and favourites). In that case, you could rely on the delayed email notifications. Or you might want to use the SE mobile app, to receive notifications. (The app is no longer developed, but some people still say they find it useful for this).
First, I think what you do is novel, to check manually for responses without depending on reply notifications. It means you care, and for that I personally appreciate you for that.
However, people are busy. They might read the comments, but they're either too busy to give proper reply, or don't have any such reply to begin with. We can't really know.
Bottom line: better not waste time on trying to figure this out, or give time frames. I got annoyed in the past here on Meta when comments I posted (usually on staff answers looking for updates) were ignored, but at some point I realized it's pointless to get annoyed, or to expect any reply.