You need to make an educated guess. Take the 'most important' (probably defined as the one that's going to take the OP furthest forward while leaving the other as a continuation to follow up) and vote for that, then comment to the OP suggesting they follow the guidelines and ask distinct individual questions (obviously providing the link to the subsequent potential duplicate for reference).
It might be that if the user has happened to ask two or more questions then they're flaunting their ignorance and would never 'play fair' - in that case it might be more appropriate to vote to close.
Bottom line, it depends.