Presently, users with reputation over some threshold don't get
rel=nofollow on their "official web site" link in their profile, which is nice. Can the same apply to links in the About Me section of the profile, for users with 3000+ rep?
Obviously, we don't want to encourage link spammers to generate
S[OFU] accounts, so setting a pretty high barrier is appropriate. But with that addressed, I would argue that whatever linkjuice a user's profile has is largely the effect of their contributions, and it'd be nice to let them have it.
It's also worth noting that under Google's new policy for nofollow logic, having nofollow links on the page damages the effect of the non-nofollow links. So if you have any stuff going on on the web besides your "official web site", you have the choice of not linking to it in your profile or hurting your "official web site" by listing it, as matters stand.