There is a question on the Ru.SO that can't be opened (at least for me under Chrome and Edge) with HTTP 400 error:
I have made a dumb question on Meta.SE to reproduce this.
Bad Request - Invalid URL
HTTP Error 400. The request URL is invalid.
In case of edit, direct URL can be used.In case of edit, direct URL can be used.
I believe it's because a "�" character in the URL of the question and the cyrillics. Only appear if the title contain both cyrillics and this character.